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[Orbital apex syndrome disclosing naso-oculo-cerebral zygomycosis]
M H Mahagne1, P Hofman, P Bedoucha
1Service de Neurologie, Hôpital Pasteur, Nice.
Revue Neurologique
|January 1, 1992
Abstract:
In a 70-year-old male patient with untreated diabetes a febrile orbital apex syndrome of rapid onset revealed a rhino-orbito-cerebral zygomycosis. Biopsies of the ethmoidal mucosa showed numerous colonies of the Rhizopus genus. Despite medical treatment (amphotericin B) and surgery (ethmoidectomy), the patient died within one week. Rhino-cerebral zygomycosis is a rare disease which occurs in diabetic and immunocompromised patients.