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Related Experiment Videos

The psoriasiform eruption induced by practolol.

R E Cochran, J Thomson, K Fleming

    Journal of Cutaneous Pathology
    |January 1, 1975
    PubMed
    Summary
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    Oral practolol can cause a psoriasiform skin eruption that mimics psoriasis clinically but shows distinct histological features of a drug eruption. Early lymphoma remains a diagnostic consideration.

    Area of Science:

    • Dermatology
    • Pharmacology
    • Histopathology

    Background:

    • Psoriasiform eruptions are inflammatory skin conditions.
    • Practolol is a beta-blocker with known side effects.

    Observation:

    • Three patients presented with psoriasiform skin eruptions after oral practolol use.
    • Clinical presentation mimicked psoriasis vulgaris.

    Findings:

    • Cutaneous histology revealed changes characteristic of a drug eruption, not typical psoriasis.
    • The histological findings raised concerns for early-stage lymphoma.

    Implications:

    • Distinguishing drug-induced psoriasiform eruptions from psoriasis is crucial.
    • Histopathological evaluation is key in diagnosing practolol-induced skin reactions.

    Related Experiment Videos

  • Consideration of drug-induced reactions is important in differential diagnosis.