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Updated: Aug 15, 2026

The Use of Reverse Phase Protein Arrays (RPPA) to Explore Protein Expression Variation within Individual Renal Cell Cancers
Published on: January 22, 2013
[Is it useful to isolate a chromophobe cell variant among carcinomas of the kidney?]
A Vieillefond1, V Paradis, P Gros
1Service d'Anatomie Pathologique, CHU Bicêtre, Le Kremlin-Bicêtre.
Abstract:
Chromophobe cell carcinoma is a little known variety of renal cell carcinoma representing 7 to 9% of all renal tumors. This tumor is confused with either clear cell carcinoma (clear subvariety) or oncocytoma (eosinophilic subvariety). Until ultrastructural and prospective studies of the prognosis of this tumor become available, it already seems important to perform colloidal iron staining to establish the differential diagnosis between oncocytoma and chromophobe cell carcinoma.
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