[Analysis of familial aggregation of serum lipids]

Twin model was studied to explain the familial aggregation of serum lipids by correlation analysis between different kinds of relatives. The phenomenon of familial aggregation was shown existing in the findings of serum cholesterol, HDL-Ch and LDL-Ch. Both effects from genetic and environmental factors were found. It is likely that there was maternal effects on cholesterol and LDL-Ch levels. The familial aggregation for TG was not very clear shown in this paper. Further study on genetic epidemiology of serum lipids is expected.