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Experience in management of diminished growth in adolescent Turner's syndrome patients
1Leiter der Abteilung für Endokrinologie, Medizinische Akademie Erfurt, Germany.
Padiatrie Und Grenzgebiete
|January 1, 1992
Abstract:
The aim in the management of patients with Turner's syndrome, besides substitution of sexual steroids, is the attempt to improve their final height. The data allow therapeutic recommendations, which, however, realize only the first intention. The final height, indeed, cannot be improved by traditional methods. Further two alternatives remain to be tested: long time low dose estrogen therapy, and high dosed HGH application.
Insights
Improving final height in Turner
Area of Science:
- Pediatric Endocrinology
- Genetics
- Growth Disorders
Background:
- Turner's syndrome affects female growth and development.
- Standard treatments focus on sexual steroid replacement.
- Improving final height remains a significant clinical challenge.
Purpose of the Study:
- To evaluate therapeutic strategies for enhancing final height in Turner's syndrome.
- To explore alternatives beyond traditional management.
Main Methods:
- Review of existing data on therapeutic interventions.
- Analysis of outcomes for different treatment approaches.
Main Results:
- Traditional methods are insufficient for significant height improvement.
- Two promising alternatives require further investigation.
Conclusions:
- Long-term, low-dose estrogen therapy is a potential option.
- High-dose Human Growth Hormone (HGH) application warrants further study.