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[Multisystemic impact in the full-term newborn with perinatal asphyxia].

O C Thompson-Chagoyán1, E Escobedo-Chávez, J L García-Vigil

  • 1División de Pediatría, Hospital General Dr. Manuel Gea González, Secretaría de Salud, México, D.F.

Boletin Medico Del Hospital Infantil De Mexico
|April 1, 1992
PubMed
Summary

Newborn infants with low Apgar scores often experience multiple systemic abnormalities, particularly affecting the brain. This study highlights a strong link between birth asphyxia and these serious health issues in newborns.

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Area of Science:

  • Neonatal Medicine
  • Pediatric Neurology
  • Perinatal Research

Context:

  • Study conducted on 30 full-term newborns admitted to a neonatal intensive care unit.
  • Infants were selected based on a 5-minute Apgar score of 5 or less.
  • Data collected between January 1989 and December 1990 at "Manuel Gea González" General Hospital.

Purpose:

  • To investigate the range and incidence of systemic disturbances in newborns with low Apgar scores.
  • To identify common organ systems affected by perinatal asphyxia.
  • To explore the relationship between asphyxia and systemic abnormalities.

Summary:

  • 29 out of 30 infants (97%) exhibited 1 to 7 systemic abnormalities.
  • The most frequent issue was brain involvement (73%), followed by metabolic and coagulation disturbances.

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  • Heart disturbances were less common.
  • No significant difference was found in the severity of abnormalities related to prenatal factors, labor, delivery, anesthesia, or Apgar score itself.

    • Impact:

    • Findings suggest a significant association between newborn asphyxia and the development of widespread systemic disturbances.
    • Highlights the critical need for early detection and management of asphyxia-related complications.
    • Informs clinical practice regarding the comprehensive assessment of newborns with compromised Apgar scores.