Presence of multinucleate cells in the papillary layer of the Macaca fuscata enamel organ

The enamel organ of Macaca fuscata from post-secretory transition to the early maturation stage of was investigated by means of light and electron microscopy. Unusual, large multinucleated cells were observed in the papillary layer. These cells contained organelles characteristic of the maturation stage ameloblast and often extended to the enamel surface, suggesting a possible origin from the ameloblast layer.