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Updated: Aug 4, 2026

Absorption of Nasal and Bronchial Fluids: Precision Sampling of the Human Respiratory Mucosa and Laboratory Processing of Samples
Published on: January 21, 2018
[Changes in spirometric values induced by nasally administered beclomethasone dipropionate in patients with perennial
R Bilancia1, F Federici, D G Ricatti
1Cattedra di Malattie dell'Apparato Respiratorio, Università degli Studi di Bari.
Abstract:
Authors showed that it's possible to control the asthmatic component in patients with persistent allergical rhinitis without bronchodilatory drugs. AA. compared two groups of ten patients: Group A has been treated with antihystaminical drugs or ketotifen per os and Disodium chromoglycate per nasal spray, Group B has been treated with the same drugs and Beclomethasone Dipropionate per nasal spray more (400 mcg a day). Respiratory functionality tests (FEV1 and MEF75) have been carried out at the beginning and at the end of the trial and the subsequent clinical parameters have been considered: dispnoea attacks, rhinorrhaea, sneezes, lost working or school days. The results of the study showed after three months of therapy a statistically significant improvement of FEV1 and MEF75 in Group B only; moreover the patients of the Group B had lower number of asthmatic attacks then patients of the Group A.
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