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Published on: May 30, 2017
Changing profile of enteric fever--in summer-91
The Journal of the Association of Physicians of India
|November 1, 1992
Summary
This study on enteric fever found that amikacin, ciprofloxacin, and ofloxacin showed 100% in vitro sensitivity. These antibiotics were highly effective in treating patients, with fever subsiding in 3-5 days.
Area of Science:
- Infectious Diseases
- Microbiology
- Clinical Medicine
Background:
- Enteric fever remains a significant global health concern.
- Understanding clinical presentations and antimicrobial resistance is crucial for effective management.
Purpose of the Study:
- To analyze the clinical features, complications, and antimicrobial sensitivity patterns of enteric fever.
- To evaluate the efficacy of specific antibiotics in treating enteric fever.
Main Methods:
- A study of 30 patients diagnosed with enteric fever.
- Clinical data collection including presenting symptoms and complications.
- In vitro antimicrobial sensitivity testing of isolated organisms.
- Assessment of clinical response to antibiotic treatment.
Main Results:
- Fever was the predominant symptom in all cases.
- Common complications included myocarditis, paralytic ileus, pneumonia, and joint effusion.
- Amikacin, ciprofloxacin, and ofloxacin demonstrated 100% in vitro sensitivity.
- Ofloxacin and ciprofloxacin achieved a 100% clinical response rate, with fever resolution in 3-5 days.
Conclusions:
- Ciprofloxacin and ofloxacin are highly effective treatments for enteric fever, exhibiting excellent clinical response rates.
- Antimicrobial stewardship is essential given varying sensitivities to older antibiotics like chloramphenicol and ampicillin.
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