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[Left ventricular function assessed by multigated blood pool single photon emission computed tomography with 99mTc].
K Murano1, M Narita, T Kurihara
1Department of Internal Medicine, Sumitomo Hospital, Osaka.
Journal of Cardiology
|January 1, 1992
Summary
Gated SPECT using 99mTc is a useful tool for assessing left ventricular function, accurately measuring left ventricular end-diastolic volume and ejection fraction compared to traditional methods.
Area of Science:
- Nuclear Medicine
- Cardiology
- Medical Imaging
Background:
- Assessing left ventricular function is crucial for diagnosing and managing heart conditions.
- Traditional methods like contrast left ventriculography have limitations.
Purpose of the Study:
- To evaluate the clinical utility of gated blood pool single photon emission computed tomography with 99mTc (gated SPECT) for assessing left ventricular function.
- To compare gated SPECT measurements with established techniques.
Main Methods:
- Gated SPECT was performed on 2 normal subjects and 18 patients with various cardiomyopathies.
- Red blood cells were labeled with 99mTc, and images were acquired across the cardiac cycle.
- Left ventricular end-diastolic volume (LVEDV), ejection fraction (LVEF), and regional wall motion were calculated and compared with contrast left ventriculography, echocardiography, and planar imaging.
Main Results:
- Gated SPECT demonstrated an excellent linear correlation for LVEDV with echocardiography (r=0.98) and contrast LVG (r=0.89).
- Regional wall motion analysis by gated SPECT showed good agreement with contrast LVG.
Conclusions:
- Gated SPECT with 99mTc is a valuable, non-invasive method for evaluating left ventricular function.
- It provides accurate measurements of LVEDV and LVEF, comparable to invasive and other non-invasive techniques.