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Cutaneous squamous cell carcinoma in Tanzania
H Amir1, M P Mbonde, J N Kitinya
1Department of Surgery, Faculty of Medicine, Muhimbili University College of Health Sciences, Dar es Salaam, Tanzania.
The Central African Journal of Medicine
|November 1, 1992
Summary
Squamous cell carcinoma is a common skin cancer in non-albino Africans, frequently affecting the lower limbs, head, and neck. Predisposing factors include chronic trauma, ulcers, scars, UV radiation, and smegma.
Area of Science:
- Dermatology
- Oncology
- Epidemiology
Background:
- Squamous cell carcinoma (SCC) is a significant skin malignancy.
- Data on SCC in non-albino African populations is less extensive compared to other demographics.
- Understanding risk factors and affected sites is crucial for early detection and prevention.
Purpose of the Study:
- To analyze the epidemiological characteristics of squamous cell carcinoma of the skin in non-albino African subjects.
- To identify common sites and predisposing factors for SCC in this population.
- To compare findings with existing literature from Africa and Black populations in America.
Main Methods:
- Retrospective review of the Tanzania Cancer Registry at Muhimbili Medical Centre.
- Analysis of patient data including age, sex, and anatomical site of SCC.
- Comparison of results with previous regional and international studies.
Main Results:
- SCC is a common and the most frequent skin cancer in the studied population.
- The peak incidence was observed in the 40-49 years age group, but cases occurred in children.
- The lower limb was the most affected site, followed by the head and neck; penis and vulva were also notably affected.
Conclusions:
- Chronic trauma, ulcers, scars, UV radiation, and smegma are identified as key predisposing factors for SCC.
- SCC affects various body parts, with specific sites showing gender predilection (scalp and lip in females).
- Findings highlight the need for targeted awareness and preventive strategies in non-albino African populations.