Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Oocyte maturation in human in vitro fertilisation programmes.

J J Tarín1, A Pellicer

  • 1Instituto Valenciano de Infertilidad, Spain.

Annals of the Academy of Medicine, Singapore
|July 1, 1992
PubMed
Summary

Oocyte immaturity in IVF cycles lowers fertilization and pregnancy rates. Strategies like adjusting hCG timing or in vitro culture can improve oocyte maturation and IVF success.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Psychosocial and environmental motivational key factors behind the parenthood desire in infertile couples at the time of COVID-19.

Journal of assisted reproduction and genetics·2024
Same author

Severe pulmonary hypertension and circulatory failure associated with Congenital syphilis. Case report.

Journal of neonatal-perinatal medicine·2024
Same author

RISEinFAMILY project: the integration of families at neonatal intensive care units (NICUs) to empower them as primary caregivers: study protocol for a stepped wedge cluster controlled trial.

Trials·2024
Same author

Allelic variants of the estrogen receptor genes and frailty phenotype in postmenopausal women.

Climacteric : the journal of the International Menopause Society·2024
Same author

Correction to: The HERA (Hyper‑response Risk Assessment) Delphi consensus for the management of hyper‑responders in in vitro fertilization.

Journal of assisted reproduction and genetics·2023
Same author

The HERA (Hyper-response Risk Assessment) Delphi consensus for the management of hyper-responders in in vitro fertilization.

Journal of assisted reproduction and genetics·2023

Area of Science:

  • Reproductive Biology
  • In Vitro Fertilisation (IVF)

Background:

  • Oocyte immaturity significantly reduces IVF efficiency, leading to lower fertilization and pregnancy rates.
  • Factors influencing oocyte maturation include stimulation protocols, hCG timing, and in vitro culture duration.
  • Assessing oocyte maturity is challenging; fertilization rate serves as an indirect indicator.

Purpose of the Study:

  • To review the factors affecting human oocyte maturation during stimulated IVF cycles.
  • To propose preventive and corrective measures for improving oocyte maturation rates.

Main Methods:

  • Literature review focusing on factors influencing oocyte maturation in IVF.
  • Analysis of the impact of stimulation protocols, hCG administration, and culture conditions.
  • Discussion of indirect assessment of oocyte maturity via fertilization rates.

Main Results:

  • Increased ovarian response to gonadotropins correlates with a higher proportion of immature oocytes.
  • Detrimental effects in high responders may be offset by a greater number of retrieved oocytes and embryo selection.
  • Delayed hCG injection or oocyte retrieval can prevent immaturity.

Conclusions:

  • Preventive measures include optimizing hCG timing and retrieval schedules.
  • Corrective strategies involve in vitro/in vivo culture, specific media additives, and granulosa cell co-culture.
  • Improving oocyte maturation is crucial for enhancing IVF treatment outcomes.

Related Experiment Videos