Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Medications in older patients.

M Hobson1

  • 1Department of Medicine, University of California, School of Medicine, San Francisco.

The Western Journal of Medicine
|November 1, 1992
PubMed
Summary

Older adults frequently experience adverse drug reactions due to multiple medications and physiological changes. Prudent prescribing and monitoring can prevent these harmful events, improving patient safety.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Swelling disease of Angora goats is characterised by panhypoproteinaemia, leukocytosis, and hyperaldosteronaemia.

Journal of the South African Veterinary Association·2026
Same author

Quantification of Angora goat beta chain haemoglobin variants using the Sebia Capillarys 2 Flex-Piercing system.

Journal of the South African Veterinary Association·2026
Same author

Poikilocytosis of Angora goats is associated with erythrocyte density and reticulocytosis.

Journal of the South African Veterinary Association·2023
Same author

Joint analysis of BICEP2/keck array and Planck Data.

Physical review letters·2015
Same author

A cosmic microwave background feature consistent with a cosmic texture.

Science (New York, N.Y.)·2007
Same author

Effects of cadmium and mercury on Na(+)-K+, ATPase and uptake of 3H-dopamine in rat brain synaptosomes.

Archives internationales de physiologie et de biochimie·1990

Area of Science:

  • Geriatrics
  • Pharmacology
  • Clinical Medicine

Background:

  • Adverse drug reactions (ADRs) are prevalent in individuals aged 65 and older, contributing to significant morbidity and mortality.
  • Factors contributing to increased susceptibility include comorbidities, polypharmacy, and age-related changes in drug metabolism and response.
  • The risk of drug interactions escalates with the number of prescribed medications.

Purpose of the Study:

  • To review the common adverse drug reactions in the elderly population.
  • To identify specific drug classes posing a high risk for older adults.
  • To provide recommendations for safer prescribing and alternative treatments.

Main Methods:

  • Review of existing literature on adverse drug reactions in the elderly.
  • Analysis of risk factors associated with polypharmacy and altered pharmacokinetics/pharmacodynamics.
  • Identification and discussion of specific high-risk medication classes.

Main Results:

  • Antihypertensive agents, anticholinergic drugs, psychoactive medications, and NSAIDs are of particular concern.
  • Some commonly prescribed drugs, like histamine H2-receptor antagonists, may be overused.
  • Data highlights the risks associated with these medications in older patients.

Conclusions:

  • Adverse drug reactions in the elderly are preventable through careful prescribing, patient education, and monitoring.
  • Alternative, safer treatment options should be considered for high-risk medications.
  • Optimizing medication management is crucial for improving health outcomes in older adults.

Related Experiment Videos