[FMD-manifestation and clinical findings (author's transl)]

Area of Science:

• Neurology
• Vascular Medicine
• Radiology

Background:

• Fibromuscular dysplasia (FMD) is a non-atherosclerotic vascular disease.
• Angiographic findings in FMD often show a characteristic
• string of beads
• appearance.
• Cerebral artery involvement in FMD can lead to significant neurological complications.

Purpose of the Study:

• To describe the etiology, manifestation, clinical findings, and therapeutic approaches for fibromuscular dysplasia.
• To report on the incidence and characteristics of FMD in cerebral angiograms.
• To propose a novel hypothesis regarding the etiology of FMD.

Main Methods:

• Retrospective analysis of 500 unselected cerebral angiograms.
• Identification and detailed review of cases diagnosed with FMD.
• Clinical data collection and review of imaging findings.

Main Results:

• Nine cases of FMD were identified, representing 1.8% of all cerebral angiograms performed.
• The study details the angiographic "string of beads" pattern in these cases.
• Clinical manifestations and therapeutic outcomes were documented.

Conclusions:

• Fibromuscular dysplasia is an important consideration in cerebrovascular disease, particularly in younger patients.
• The "string of beads" sign is a key diagnostic feature of FMD on cerebral angiography.
• Further research is warranted to elucidate the precise etiology of FMD.