Related Experiment Video
Updated: Aug 13, 2026

Monitoring Kinase and Phosphatase Activities Through the Cell Cycle by Ratiometric FRET
Published on: January 27, 2012
Okadaic acid--a valuable new tool for the study of signal transduction and cell cycle regulation?
1Cancer Center, University of California, San Diego, La Jolla 92093-0636.
Abstract:
Okadaic acid is beginning to find its way into laboratories that study cellular control of gene expression and proliferation. By virtue of its specific inhibitory effects on certain protein phosphatases it seems to be a powerful tool for the analysis of regulatory phosphorylation-dephosphorylation events. Here, some of the important new findings with the use of this drug are summarized, and a few potential drawbacks of its application discussed.
More Related Videos
Related Concept Videos
Positive Regulator Molecules
Positive Regulator Molecules
Inhibition of Cdk Activity
Anaphase Promoting Complex
MAPK Signaling Cascades
Inhibition of CDK Activity

