A new cyclopyrophosphate as a bacterial antistressor?
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D Ostrovsky1, I Shipanova, L Sibeldina
1Bakh Institute of Biochemistry, USSR Academy of Sciences, Moscow.
FEBS Letters
|February 24, 1992
Abstract:
In a number of bacteria an unusual glycosyl pyrophosphate (31P NMR signal chemical shift at about -15 ppm) was detected when the cells were subjected to oxidative stress. This substance from Brevibacterium ammoniagenes has now been identified as 2-methyl-butan-1,2,3,4,-tetraol-2,4-cyclopyrophosphate, which is accumulated in the cell under certain conditions in concentrations of of about 50 mM. It is now suggested that this compound is the long sought after bacterial antistressor.