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Published on: November 30, 2010
Abstract:
Thirty cases of anogenital moniliasis were studied. Only five followed oral use of broad spectrum antibiotics. Although anogenital pruritus commonly follows the use of such drugs, it is rarely proved to be moniliasis, which is clinically diagnosed by symptoms of intertriginous denudation with satellite vesicopustules or the presence of cheesy, grossly detachable plaques. The diagnosis may be confirmed by microscopic observation of delicate hyphae and clusters of spores, or of chlamydospores on corn meal agar. One per cent aqueous gentian violet, 0.1 per cent gentian violet jel, or locally applied mercurials are the most effective forms of treatment, but effort must also be directed against predisposing factors (obesity, hyperhidrosis, oral or local use of broad spectrum antibiotics, diabetes and pregnancy).
Insights
Anogenital moniliasis, a fungal infection, is often misdiagnosed. Effective treatment involves topical antifungals and addressing predisposing factors like antibiotic use and diabetes.
Area of Science:
- Dermatology
- Mycology
- Infectious Diseases
Background:
- Anogenital pruritus is a common symptom following broad-spectrum antibiotic use.
- Moniliasis is often clinically diagnosed but can be confirmed microscopically.
Purpose of the Study:
- To investigate cases of anogenital moniliasis.
- To identify predisposing factors and effective treatments for anogenital candidiasis.
Main Methods:
- Clinical diagnosis based on characteristic symptoms like denudation and plaques.
- Microscopic confirmation of fungal elements (hyphae, spores).
- Culture on corn meal agar for chlamydospore identification.
Main Results:
- Thirty cases of anogenital moniliasis were studied.
- Only five cases were linked to prior oral broad-spectrum antibiotic use.
- Predisposing factors included obesity, hyperhidrosis, antibiotic use, diabetes, and pregnancy.
Conclusions:
- Effective treatments include 1% aqueous gentian violet, 0.1% gentian violet gel, and topical mercurials.
- Addressing predisposing factors is crucial for managing anogenital moniliasis.
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