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Hospitalizations for coronary artery disease among patients with systemic lupus erythematosus

Christine M Thorburn1, Michael M Ward

  • 1Stanford University School of Medicine, Stanford, California, USA.

Arthritis and Rheumatism
|September 18, 2003
PubMed

Insights

Coronary artery disease (CAD) is a significant comorbidity in systemic lupus erythematosus (SLE) patients. While CAD hospitalizations occurred, they were less frequent than SLE, infections, or renal failure complications.

Area of Science:

  • Cardiology
  • Rheumatology
  • Health Services Research

Background:

  • Systemic lupus erythematosus (SLE) patients face higher coronary artery disease (CAD) risks.
  • The actual burden of CAD hospitalizations in SLE patients remains understudied.

Purpose of the Study:

  • To estimate the burden of CAD hospitalizations among US patients with SLE in 1998.
  • To compare CAD hospitalization rates with other reasons for admission in SLE patients.

Main Methods:

  • Utilized the Nationwide Inpatient Sample (NIS) database for 1998.
  • Identified hospitalizations for CAD (acute myocardial infarction, unstable angina, procedures) in SLE patients.
  • Compared CAD hospitalization frequency against SLE, infections, and renal failure complications.

Main Results:

  • Estimated 4,951 hospitalizations for CAD among SLE patients in 1998.
  • Acute myocardial infarction accounted for 1,763 of these CAD hospitalizations.
  • CAD hospitalizations were less common than SLE, infections, or chronic renal failure complications, particularly in younger women.

Conclusions:

  • Coronary artery disease (CAD) is a notable comorbidity in systemic lupus erythematosus (SLE).
  • However, CAD is not the primary driver for hospitalizations in SLE patients compared to SLE itself, infections, or renal issues.
Abstract

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