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Failure of adrenocorticotrophic hormone to release serum amyloid A in cattle
J H van der Kolk1, S P Alsemgeest, T Wensing
1Faculty of Veterinary Medicine, State University of Utrecht, The Netherlands.
Research in Veterinary Science
|January 1, 1992
Abstract:
The objective of this study was to determine whether adrenocorticotrophic hormone plays a direct role in the secretion of serum amyloid A (SAA) in cattle. Seven lactating Holstein-Friesian cows were given either saline or 25 iu adrenocorticotrophic hormone (ACTH) intravenously at 09.00 in a two factor crossover design. Plasma cortisol concentrations had increased significantly by one hour after the injection of ACTH, whereas the SAA level had not increased by 24 hours after injection. It is concluded that in cattle adrenocorticotrophic hormone has no direct influence on the release of SAA by the hepatocyte.