Rational management of uveitis

Endogenous uveitis is an important cause of blindness in young adults. The need for a comprehensive search for an aetiological 'antigen' is stressed. A source of adjuvant, disturbance in host immunology and any associated syndromes are also sought. Treatment then involves elimination of 'antigen', suppression of host hypersensitivity and the enhanced vascular permeability, and improvement of host resistance. The value of antihistamine and antiserotonin drugs in successful treatment is emphasised.