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Related Experiment Videos

Cocaine-associated panic attacks in methadone-maintained patients.

M I Rosen1, T Kosten

  • 1Department of Psychiatry, Yale University, New Haven, Connecticut 06511.

The American Journal of Drug and Alcohol Abuse
|January 1, 1992
PubMed
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Panic attack incidence in methadone patients rose significantly, linked to cocaine use. These patients show distinct differences in hospitalization and medical conditions compared to others.

Area of Science:

  • Clinical Psychiatry
  • Addiction Medicine
  • Pharmacology

Background:

  • Panic attacks are a concern in patients undergoing methadone maintenance therapy.
  • A notable increase in panic attack incidence has been observed over the past decade.
  • Cocaine use is a potential contributing factor to this rise.

Purpose of the Study:

  • To investigate the increasing incidence of panic attacks in methadone-maintained patients.
  • To explore the association between cocaine use and panic attacks in this population.
  • To identify unique characteristics of patients experiencing cocaine-associated panic attacks.

Main Methods:

  • Retrospective analysis of patient data over a 10-year period.
  • Comparison of panic attack incidence rates.

Related Experiment Videos

  • Analysis of clinical and demographic factors differentiating patient groups.

    • Main Results:

    • Panic attack incidence in methadone-maintained patients increased from 1% to 6-13% over 10 years.
    • Cocaine use is strongly associated with this observed increase.
    • Patients with cocaine-associated panic attacks exhibit higher rates of psychiatric hospitalization and medical illness compared to other panic patients.
    • No significant differences were found in depression, other drug use, or agoraphobia.

    Conclusions:

    • The rising incidence of panic attacks in methadone patients is a significant clinical issue.
    • Cocaine use is a key factor associated with increased panic attacks in this cohort.
    • Cocaine-associated panic attacks present with distinct clinical profiles, particularly concerning medical and psychiatric comorbidities.