Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[VIPoma: surgical treatment].

F Procacciante1, P Picozzi, A Fantini

  • 1Cattedra di Patologia Chirurgica, Università degli Studi di Roma La Sapienza.

Minerva Chirurgica
|February 1, 1992
PubMed
Summary

This study details a pancreatic VIPoma case with liver metastasis, managed with a synthetic somatostatin analog (SMS 201/995) for two years. The analog effectively controlled diarrhea, aiding disease management.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Veterinary response to non-epidemic disasters: the experience of the Istituto Zooprofilattico Sperimentale dell'Abruzzo e del Molise "G. Caporale" after the 2009 earthquake in L'Aquila, Italy.

New Zealand veterinary journal·2025
Same author

Characterization of the O/ME-SA/Ind-2001d foot-and-mouth disease virus epidemic recorded in the Maghreb during 2014-2015.

Transboundary and emerging diseases·2022
Same author

An innovative in-situ DRAINage system for advanced groundwater reactive TREATment (in-DRAIN-TREAT).

Chemosphere·2021
Same author

Exploring the human hair follicle microbiome.

The British journal of dermatology·2020
Same author

Measurement of differential cross sections for inclusive isolated-photon and photon+jet production in proton-proton collisions at <math> </math>.

The European physical journal. C, Particles and fields·2019
Same author

Search for rare decays of <math></math> and Higgs bosons to <math></math> and a photon in proton-proton collisions at <math></math> = 13 <math></math>.

The European physical journal. C, Particles and fields·2019

Area of Science:

  • Oncology
  • Endocrinology
  • Gastroenterology

Background:

  • Pancreatic VIPomas are rare neuroendocrine tumors, often malignant and diagnosed late with widespread metastasis.
  • Surgical resection is the primary treatment, but rarely feasible due to advanced disease at diagnosis.

Observation:

  • A patient with a pancreatic VIPoma and extensive hepatic metastasis underwent a partial pancreasectomy due to tumor infiltration.
  • Treatment included a synthetic somatostatin analog (SMS 201/995) for symptom control and monitoring with neuron-specific enolase (NSE) serum assays.

Findings:

  • The synthetic somatostatin analog (SMS 201/995) provided satisfactory control of diarrhea, a common VIPoma symptom.
  • Neuron-specific enolase (NSE) serum levels effectively monitored disease progression during the follow-up period.

Related Experiment Videos

Implications:

  • Synthetic somatostatin analogs are indicated for managing VIPoma symptoms, particularly diarrhea.
  • NSE monitoring is a valuable tool for assessing treatment response and disease evolution in VIPoma patients.
  • Partial surgical resection combined with medical management can be a viable strategy for advanced pancreatic VIPomas.