Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Poliomyelitis case confirmation: characteristics for use by national eradication programmes.

R J Biellik1, H Bueno, J M Olive

  • 1EPI/WHO, Kathmandu, Nepal.

Bulletin of the World Health Organization
|January 1, 1992
PubMed
Summary

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Risks and benefits of sharing patient information on social media: a digital dilemma.

European heart journal. Digital health·2024
Same author

Editor's Choice - Frailty and the management of patients with acute cardiovascular disease: A position paper from the Acute Cardiovascular Care Association.

European heart journal. Acute cardiovascular care·2018
Same author

Measles and Rubella Global Strategic Plan 2012-2020 midterm review.

Vaccine·2018
Same author

Assessment of the knowledge and perception of support of patients with heart failure SOPICA study IN SPAIN.

Revista clinica espanola·2016
Same author

Optimisation of antithrombotic therapy in patients with acute coronary syndrome to reduce bleeding episodes.

International journal of clinical practice·2015
Same author

New-onset atrial fibrillation and prognosis in nonagenarians after acute myocardial infarction.

Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation·2013

No single case definition perfectly identifies poliomyelitis, but targeted investigation strategies can improve accuracy in resource-limited settings. Prioritizing specific symptoms and demographics aids in accurate polio diagnosis and eradication efforts.

Area of Science:

  • Epidemiology
  • Virology
  • Public Health

Background:

  • National poliomyelitis eradication programs introduced sensitive case definitions to prevent missing cases.
  • Low specificity of early definitions led to false-positive diagnostic errors.
  • Evaluating case definitions for optimal sensitivity and specificity is crucial for disease control.

Purpose of the Study:

  • To study characteristics of confirmed poliomyelitis cases using extensive data from Brazil (1987-88).
  • To epidemiologically evaluate potential case definitions maximizing both sensitivity and specificity.
  • To compare confirmed poliomyelitis cases with rejected non-polio cases.

Main Methods:

  • Analysis of 1620 acute, flaccid paralysis cases reported in Brazil.
  • Inclusion criteria: age <10 years, investigation within 15 days of onset, complete laboratory specimens.
Keywords:
Age FactorsAmericasAntibodiesBiologyBrazilClinical ResearchComparative StudiesDelivery Of Health CareDemographic FactorsDeveloping CountriesDiseasesExaminations And DiagnosesFollow-up StudiesHealthHealth ServicesHematologic TestsImmunityImmunity, ActiveImmunizationImmunologic FactorsInfantLaboratory Examinations And DiagnosesLaboratory ProceduresLatin AmericaMethodological StudiesPhysiologyPopulationPopulation CharacteristicsPrimary Health CareResearch MethodologySouth AmericaStudiesVaccinesViral Diseases--prevention and controlYouth

Related Experiment Videos

  • Comparison of wild poliomyelitis virus isolation-confirmed cases versus non-polio cases.

    • Main Results:

    • No single practical case definition achieved both high sensitivity and high specificity.
    • Recommended priorities for resource-limited endemic countries: cases <5 years, prodromal fever, non-quadrilimb involvement, short progression, recent local confirmation.
    • Alternative definition for countries without lab resources: acute flaccid paralysis with lower limb involvement and 60-day sequelae.

    Conclusions:

    • Optimizing case definitions is essential for effective poliomyelitis surveillance and eradication.
    • Resource-limited settings should prioritize specific clinical and epidemiological features for case investigation.
    • Countries nearing eradication can refine case rejection criteria based on laboratory confirmation and clinical presentation.