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Related Experiment Videos

The fundus in mongolism.

A Ahmad, R C Pruett

    Archives of Ophthalmology (Chicago, Ill. : 1960)
    |May 1, 1976
    PubMed
    Summary
    This summary is machine-generated.

    Ophthalmic findings in Down syndrome (mongolism) include a rosy optic disc, reduced pigmentation, and choroidal vascular changes. Retinal detachment, often due to dialysis and trauma, is a significant complication requiring early diagnosis and prevention strategies.

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    Area of Science:

    • Ophthalmology
    • Genetics
    • Medical Research

    Background:

    • Down syndrome (mongolism) is a genetic disorder with various associated health issues.
    • Ocular abnormalities are common in individuals with Down syndrome.
    • Understanding these abnormalities is crucial for patient care and management.

    Purpose of the Study:

    • To investigate and document the common fundus abnormalities in patients with Down syndrome.
    • To identify potential predisposing factors and complications, such as retinal detachment.
    • To suggest methods for prevention and early diagnosis of ocular complications.

    Main Methods:

    • Indirect ophthalmoscopy was used to examine the fundus.
    • The study included 63 eyes from 32 karyotyped patients with Down syndrome.

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  • Additional eyes with retinal detachment were analyzed for causes and treatment outcomes.

    • Main Results:

    • Common findings included a rosy optic disc with increased retinal vessels, generalized hypopigmentation, pigment epithelial atrophy, and choroidal vascular changes.
    • These features are suggestive of Down syndrome but not definitive.
    • Retinal detachment, particularly retinal dialysis, was observed in 11 eyes, with trauma as a suspected factor.

    Conclusions:

    • Specific fundus findings can be associated with Down syndrome.
    • Retinal detachment is a serious complication that warrants attention.
    • Early diagnosis and preventive measures are recommended for ocular complications in Down syndrome patients.