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Updated: Oct 12, 2026

Assessment of Neuromuscular Function Using Percutaneous Electrical Nerve Stimulation
Published on: September 13, 2015
Neuromuscular hyperexcitability features in patients suffering from musculoskeletal pain: a neuroepidemiologic survey
P H Jansen1, J A van Dijck, A L Verbeek
1Department of Neurology, Gelderse Vallei Hospital, Wageningen, The Netherlands.
Abstract:
We studied the reported frequencies of clinical complaints of neuromuscular hyperexcitability (muscle cramps and fasciculations) in random samples of 527 Dutch adults, who were and 253 Dutch adults, who were not suffering from musculoskeletal pain and tenderness. Data were collected by telephone-interview and by self-administered questionnaire. Muscle cramps and fasciculations were recorded more frequently in the category that suffered from musculoskeletal pain (p less than 0.001). This association warrants further investigation into the possible intrinsic role of neuromuscular hyperexcitability in musculoskeletal pain and primary fibromyalgia.
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