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Ultrasonic Assessment of Myocardial Microstructure
Published on: January 14, 2014
Echocardiographic studies of abnormalities associated with coarctation of the aorta
Insights
Echocardiography revealed that over half of patients with coarctation of the aorta have bicuspid aortic valves, often associated with aortic regurgitation. Some patients also showed signs of idiopathic hypertrophic subaortic stenosis.
Area of Science:
- Cardiology
- Pediatric Cardiology
- Cardiac Imaging
Background:
- Coarctation of the aorta is a congenital heart defect.
- Associated cardiac anomalies are common in patients with coarctation of the aorta.
- Echocardiography is a key diagnostic tool for evaluating aortic and valvular abnormalities.
Purpose of the Study:
- To assess the prevalence of bicuspid aortic valves and other cardiac abnormalities in patients with coarctation of the aorta using echocardiography.
- To correlate echocardiographic findings with other diagnostic methods.
Main Methods:
- Echocardiograms were performed on 36 patients (aged 4-36 years) diagnosed with coarctation of the aorta.
- Aortic valve morphology was assessed using the Eccentricity Index.
- Mitral valve motion and aortic root echoes were analyzed.
- Findings were compared with available angiographic and catheterization data.
Main Results:
- Nineteen patients (53%) exhibited marked diastolic eccentricities of the aortic valves (Eccentricity Index > 1.5), indicative of bicuspid aortic valves.
- Five patients with bicuspid aortic valves showed mitral valve diastolic flutter, suggesting aortic regurgitation.
- Four patients (11%) had findings suggestive of idiopathic hypertrophic subaortic stenosis (IHSS), including abnormal systolic anterior motion of the mitral valve and asymmetric septal hypertrophy.
- Catheterization confirmed IHSS in one patient.
- Two patients (5.6%) presented with mitral valve prolapse.
Conclusions:
- Echocardiography is effective in identifying bicuspid aortic valves in patients with coarctation of the aorta.
- Bicuspid aortic valves are frequently associated with aortic regurgitation and other cardiac anomalies in this population.
- Echocardiography can also detect other significant conditions like IHSS and mitral valve prolapse in patients with coarctation of the aorta.
Abstract:
Echocardiograms were performed in thirty-six patients (aged 4 to 36 years) with proven coarctation of the aorta. Nineteen patients (53%) were found to have marked diastolic eccentricities of their aortic valves (Eccentricity Index greater 1.5), indicating the presence of bicuspid aortic valves. One of these patients also had multilayered aortic root echoes in diastole. Five patients had angiographic proof of their aortic valve morphologies which corroborated the echo findings. Five patients with bicuspid aortic valves showed mitral valve diastolic flutter indicative of aortic regurgitation. Idiopathic hypertrophic subaortic stenosis (IHSS) was suspected in four patients (11%) with abnormal systolic anterior motion of the mitral valve; three of these patients also had asymmetric septal hypertrophy. There was catheterization proof of IHSS in one patient. Two patients (5.6%) demonstrated mitral valve proplapse.
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