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Primary vaginal adenocarcinoma of the intestinal type associated with adenosis
H Yaghsezian1, J P Palazzo, G C Finkel
1Department of Pathology and Cell Biology, Thomas Jefferson University Hospital, Philadelphia, Pennsylvania 19107.
Gynecologic Oncology
|April 11, 1992
Abstract:
Primary vaginal adenocarcinoma unrelated to intrauterine hormone exposure is very uncommon. We report a case of a 52-year-old woman who presented with primary vaginal adenocarcinoma that showed intestinal differentiation with prominent papillary formations and numerous papillary and villous features with prominent goblet cells. There was vaginal adenosis in the immediate vicinity of the tumor. To our knowledge, this is the first reported case of a primary vaginal adenocarcinoma of the intestinal type associated with adenosis in a patient unexposed to prenatal diethylstilbesterol.