Personality features and platelet 3H-imipramine binding
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P Castrogiovanni1, I Maremmani, A Di Muro
1Institute of Psychiatry, University of Pisa, Italy.
Neuropsychobiology
|January 1, 1992
Abstract:
In an attempt to provide further information on the functions of the serotonergic system in humans, we investigated the possible correlation between a peripheral serotonergic marker, such as platelet 3H-imipramine binding, and the Minnesota Multiphasic Personality Inventory (MMPI) items and scales in a group of 20 healthy subjects. The results showed the presence of significant positive correlation between the maximum binding capacity, a measure of the number of 3H-imipramine sites, and 17 MMPI items suggestive of personality features of self-certainty, feeling of well-being and sense of reality.