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Related Experiment Videos

Bromide intoxication.

D L Trump, M C Hochberg

    The Johns Hopkins Medical Journal
    |April 1, 1976
    PubMed
    Summary
    This summary is machine-generated.

    Bromide intoxication, though rare, presents with varied neuropsychiatric symptoms. Treatment with saline and diuretics is effective, but its declining incidence reflects reduced bromide use.

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    Area of Science:

    • Neurology
    • Toxicology
    • Internal Medicine

    Background:

    • Bromide intoxication is an uncommon condition.
    • This report reviews 23 years of patient data from Johns Hopkins Hospital.

    Observation:

    • Patients exhibit variable neuropsychiatric symptoms.
    • Clinical indicators include impaired sensorium, fever, rash, and abnormal serum chloride.
    • A history of proprietary drug abuse may be present.

    Findings:

    • Treatment with saline administration, often combined with diuretics (mercurial, thiazide, or loop), proved uniformly effective.
    • The incidence of bromide intoxication has declined significantly over the study period.

    Implications:

    • The decrease in bromide intoxication cases is attributed to reduced physician prescription of bromides.
  • Reduced availability of over-the-counter bromide-containing products also contributes to the declining incidence.
  • Awareness of potential neuropsychiatric symptoms remains crucial for diagnosing this rare disorder.