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Replication of human herpesvirus 6 in epithelial cells in vitro
A Simmons1, Y Demmrich, A La Vista
1Division of Medical Virology, Institute of Medical and Veterinary Science, Adelaide, Australia.
The Journal of Infectious Diseases
|July 1, 1992
Abstract:
Mink lung epithelial (NBL-7) cells were shown to be permissive for human herpesvirus 6 (HHV-6) by four independent methods of analysis: detection of infectious virus, viral antigens, viral DNA sequences, and herpesvirus particles. Infection was serially passaged, with minimal cytopathology, for several months demonstrating for the first time that a cell of epithelial origin can support HHV-6 replication.