Related Experiment Videos
Comparison of EBV-infectivity measured by EBNA-induction and immortalization of human B-cells
1Department of Cellular and Molecular Biology Research, Miles, Inc., Berkeley, CA 94701.
Abstract:
Epstein-Barr virus (EBV) infectivity was measured by two different systems. One was EBV-specific antigen (EBNA) induction in EBV-negative BJAB cells, the other was immortalization of human peripheral blood B-lymphocytes upon EBV infection. Because the sensitivity of the EBNA-induction assay, which takes 2-3 days, was similar with that of B-cell immortalization, which takes 6-8 weeks, the former can be used for the rapid and convenient determination of EBV-infectivity.