[Bone defect filling material in jaw bones using tricalcium phosphate].

Area of Science:

• Biomaterials Science
• Oral and Maxillofacial Surgery
• Regenerative Medicine

Context:

• Cystic defects in the maxilla and mandible present treatment challenges.
• The need for effective bone graft materials is critical in oral surgery.
• Biocompatible and resorbable materials are preferred for bone regeneration.

Purpose:

• To evaluate Beta-Tricalcium-phosphate (β-TCP) as a filling material for cystic jaw defects.
• To assess the biocompatibility and osseous integration of β-TCP.
• To determine the efficacy of β-TCP in promoting bone regeneration.

Summary:

• Beta-Tricalcium-phosphate (β-TCP) granulate was used in 51 patients with cystic jaw defects.
• The material demonstrated biocompatibility, causing no immunologic reactions.
• Radiological and histological analyses confirmed β-TCP resorption and replacement by new bone formation.
• In three cases, the material required removal, indicating potential complications.

Impact:

• Beta-Tricalcium-phosphate (β-TCP) is a viable alternative bone graft material for maxillomandibular cystic defects.
• Successful osseous integration highlights the potential of β-TCP in bone defect repair.
• Further research may optimize its application and minimize adverse events.