Related Experiment Videos
Synovial sarcoma of the head and neck
R P Bukachevsky1, R L Pincus, F G Shechtman
1Department of Otolarygnology-Head and Neck Surgery, New York Eye & Ear Infirmary, New York Medical College, New York.
Head & Neck
|January 1, 1992
Summary
Primary synovial sarcoma is a rare head and neck tumor. Multimodality treatment, including surgery and radiation, is effective for these rare tumors.
Area of Science:
- Oncology
- Head and Neck Surgery
Background:
- Primary synovial sarcoma of the head and neck is exceptionally rare, with fewer than 75 reported cases.
- This study details 7 additional cases, expanding the literature on this unusual tumor presentation.
Observation:
- Cases presented with symptoms including enlarging cervical mass, voice changes, and dysphagia.
- CT imaging showed solitary, nonhomogenous tumors ranging from 3 to 7 cm.
- Microscopic examination consistently revealed a biphasic cellular pattern confirmed by immunohistochemistry.
Findings:
- Multimodality treatment involving surgery and postoperative radiation therapy was employed.
- Three patients also received chemotherapy as part of their treatment regimen.
- Initial pathology reports were inaccurate in 3 cases, highlighting the need for clinical suspicion.
Implications:
- Clinical suspicion is crucial for accurate diagnosis of head and neck synovial sarcoma.
- Multimodality treatment approaches demonstrate efficacy in managing these rare malignancies.
- Further research into optimal treatment strategies for head and neck synovial sarcoma is warranted.