Detection of herpes simplex virus in gingival tissue
1Virology Department, Hebrew University Hadassah Medical School, Jerusalem, Israel.
Journal of Periodontology
|June 1, 1992
Abstract:
The presence of herpes simplex virus (HSV) antigens was shown by immunofluorescence staining in 26 of 66 (39.3%) specimens of clinically healthy gingiva, but only one sample contained infectious virus. HSV DNA sequences were clearly identified in intact gingival cells by dot blot hybridization in one specimen, and a weak pattern in a second one. Both specimens harbored viral antigens. These findings of viral genome and protein expression suggest that the virus is present in the latent form in the gingiva.
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