Related Experiment Videos
Acute effects of cadmium on the renin angiotensin system in rats
1Division of Pharmacology, Central Drug Research Institute, Lucknow, India.
Biochemical Pharmacology
|July 7, 1992
Abstract:
The effect of cadmium acetate (1 mg/kg i.p.) on the renin angiotensin system was examined in male Sprague-Dawley rats. Blood pressure, plasma renin activity (PRA) and serum angiotensin converting enzyme (ACE) levels were determined in the rats. Cadmium acetate produced a hypertensive response which was not associated with elevated PRA. However, ACE levels in the serum were significantly decreased in the cadmium-treated group as compared with normal controls (P less than 0.01).