Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Papillomaviruses and human oncogenesis.

L Gissmann1

  • 1Forschungsschwerpunkt Angewandte Tumorvirologie, Deutsches Krebsforschungszentrum, Heidelberg, Germany.

Current Opinion in Genetics & Development
|February 1, 1992
PubMed
Summary

Recent research advances human papillomavirus (HPV) understanding. Scientists now better comprehend the roles of E6 and E7 oncoproteins in genital tumors and host responses to HPV infection.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Vaccination against HPV-Associated Neoplasias: Recommendations from the Current S3 Guideline of the HPV Management Forum of the Paul-Ehrlich Society - AWMF Guidelines, Registry No. 082-002 (short version), valid until Dec. 31st, 2018.

Geburtshilfe und Frauenheilkunde·2016
Same author

[Vaccination against HPV-associated neoplasias].

Laryngo- rhino- otologie·2014
Same author

[Prevention of HPV-associated neoplasias by vaccination - short version of the German S3 (level 3) guideline].

Deutsche medizinische Wochenschrift (1946)·2010
Same author

Short version of the German evidence-based Guidelines for prophylactic vaccination against HPV-associated neoplasia.

Vaccine·2009
Same author

[Recurrent respiratory papillomatosis: indication for HPV vaccination?].

Deutsche medizinische Wochenschrift (1946)·2009
Same author

Loss of p53 or p73 in human papillomavirus type 38 E6 and E7 transgenic mice partially restores the UV-activated cell cycle checkpoints.

Oncogene·2007

Area of Science:

  • Oncology
  • Virology
  • Dermatology

Background:

  • Human papillomaviruses (HPVs) are linked to malignant genital tumors.
  • The E6 and E7 oncoproteins play crucial roles in HPV-associated cancers.
  • Understanding host responses to HPV infection is vital.

Purpose of the Study:

  • To summarize recent advances in understanding HPV oncoproteins E6 and E7.
  • To detail new findings on keratinocyte and individual responses to HPV infection.

Main Methods:

  • Review of recent scientific literature on HPV E6 and E7 oncoproteins.
  • Analysis of studies investigating cellular and systemic responses to HPV.

Main Results:

  • Significant progress in elucidating the functions of HPV E6 and E7 oncoproteins.
  • New data available on keratinocyte responses to HPV.
  • Enhanced understanding of the host's immune and cellular reactions to HPV infection.

Conclusions:

  • Continued research is deepening our knowledge of HPV pathogenesis.
  • Understanding oncoprotein function and host response is key to developing targeted therapies for HPV-related malignancies.

Related Experiment Videos