[Effects of insulin on the protein metabolism of carp liver]

Studies on protein metabolism in carp liver under influence of insulin injections have been carried out. Protein turn-over is significantly reduced by insulin; in fact, half-life of tritiated proteins is increased to twice the controls value. Furthermore, electron microscopic studies of nucleolus suggest an enhancement of proteosynthesis. Our findings, similar to those generally described in mammals are in good accordance with the rise of protein amount. With regard to the strong drop of carpe liver glycogen after insulin injection, which had been previously reported, these data could thus indicate that such a paradoxical effect of the hormone is limited to the glycogen metabolism.