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The antigenic potency of non-infectious poliomyelitis virus as determined by its liberating effect on active virus

U KRECH

    The Journal of Experimental Medicine
    |March 1, 1955
    PubMed

    Keywords:
    ANTIGENS AND ANTIBODIESPOLIOMYELITIS VIRUS

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    Poliomyelitis

    Poliomyelitis is caused by poliovirus, a small, non-enveloped, positive-sense RNA virus of the Picornaviridae family and Enterovirus genus. Transmission occurs primarily via the fecal-oral route, often through ingestion of contaminated water or food. The virus initially replicates in the oropharynx and intestinal mucosa, particularly in lymphoid tissues such as the tonsils, Peyer’s patches, and regional lymph nodes. Primary viremia follows, allowing dissemination throughout the body.In most...