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Excitatory amino acid receptors and disease
1Department of Neurology, Institute of Psychiatry, De Crespigny Park, Denmark Hill, London, UK.
Current Opinion in Neurology and Neurosurgery
|August 1, 1992
Abstract:
Recent advances in the molecular biology of excitatory amino acid receptors are reviewed. Evidence that drugs blocking the excitatory action of glutamate at the N-methyl-D-aspartate (NMDA) and non-NMDA receptors may be of clinical use in epilepsy, Parkinson's disease, cerebral ischaemia and trauma, acquired immune deficiency syndrome (AIDS) encephalopathy and neuropathic pain is summarized.