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Effect of Sp-cAMP on sperm motility in patients with unexplained infertility
1Division of Urological Surgery, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115.
Andrologia
|January 1, 1992
Abstract:
Sperm motility is one of the most important semen parameters affecting the fertility of an individual. Sp-cAMP, a thiophosphate analogue of c-AMP, is a phosphodiesterase inhibitor controlling the intracellular c-AMP levels which in turn influences sperm motility. The results in our laboratory on a group of suspected subfertile men and fertile donors showed significant enhancement of sperm motility after incubation of washed sperm with various doses of Sp-cAMP.