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Related Experiment Videos

Sensory nerve abnormalities in brachial plexopathy.

M Rubin1, D J Lange

  • 1Department of Neurology and Neuroscience, New York Hospital-Cornell Medical Center, New York 10021.

European Neurology
|January 1, 1992
PubMed
Summary
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Sensory nerve action potential (SNAP) amplitude is frequently abnormal in brachial plexopathies (BP), indicating nerve damage. Studying multiple sensory nerves improves diagnostic accuracy for BP.

Area of Science:

  • Neurology
  • Neurophysiology
  • Clinical Electrophysiology

Background:

  • Brachial plexopathies (BP) involve damage to the brachial plexus nerves.
  • Axonal degeneration in distal nerve segments is a hallmark of BP.
  • Sensory nerve action potential (SNAP) amplitude abnormalities are expected in BP.

Purpose of the Study:

  • To evaluate the diagnostic utility of SNAP amplitude in patients with brachial plexopathies.
  • To determine the prevalence of abnormal SNAP amplitudes across different types of BP.
  • To assess if testing multiple sensory nerves improves diagnostic yield.

Main Methods:

  • Retrospective analysis of 56 patients diagnosed with brachial plexopathy.
  • Recording of sensory nerve action potential (SNAP) amplitudes.

Related Experiment Videos

  • Categorization of BP based on affected nerve distribution (diffuse, upper trunk, lower trunk/medial cord).

    • Main Results:

    • 88% of diffuse BP patients had abnormal median or ulnar SNAP.
    • 60% of upper trunk BP patients showed abnormal SNAP (median, radial, or lateral antebrachial cutaneous).
    • 75% of lower trunk/medial cord BP patients had abnormal SNAP (median or ulnar).
    • Overall, 82.5% of patients exhibited abnormal SNAP when nerves in symptomatic regions were tested.

    Conclusions:

    • Abnormal SNAP amplitudes are highly prevalent in brachial plexopathies.
    • Testing multiple sensory nerves, particularly in symptomatic areas, significantly enhances the diagnostic yield of SNAP for BP.
    • SNAP amplitude assessment is a valuable tool for diagnosing and characterizing brachial plexopathies.