Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Numerical chromosome aberrations in fibrothecoma.

P Dal Cin1, P Moerman, I De Wever

  • 1Center for Human Genetics, University of Leuven, Belgium.

Tumori
|April 30, 1992
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Posterior scalp defects in Opitz syndrome. Another symptom related to a defect in midline development.

Clinical genetics·1992
Same author

The primary sequence and the subunit structure of mouse alpha-2-macroglobulin, deduced from protein sequencing of the isolated subunits and from molecular cloning of the cDNA.

European journal of biochemistry·1992
Same author

Leukaemic intermediate lymphocytic lymphomas: analysis of twelve cases diagnosed by morphology.

Leukemia & lymphoma·1992
Same author

Developmental changes in heparan sulfate expression: in situ detection with mAbs.

The Journal of cell biology·1992
Same author

Trisomy 7 and trisomy 10 characterize subpopulations of tumor-infiltrating lymphocytes in kidney tumors and in the surrounding kidney tissue.

Proceedings of the National Academy of Sciences of the United States of America·1992
Same author

Cell surface heparan sulfate proteoglycans from human vascular endothelial cells. Core protein characterization and antithrombin III binding properties.

The Journal of biological chemistry·1992

Cytogenetic analysis revealed numerical chromosome abnormalities in a fibrothecoma. An extra copy of chromosome 12 in mesenchymal tumors suggests a common embryonic origin, particularly in the female genital tract.

Area of Science:

  • Reproductive medicine
  • Cytogenetics
  • Oncology

Background:

  • Fibrothecomas are rare ovarian tumors.
  • Cytogenetic analysis is crucial for understanding tumor development.
  • Mesenchymal tumors can arise from various tissues.

Observation:

  • A 7-day-old fibrothecoma culture was analyzed.
  • The culture exhibited numerical chromosome abnormalities.

Findings:

  • The fibrothecoma displayed a karyotype of 57, XX, +4, +5, +6, +10, +12, +12, +14, +17, +18, +19, +20.
  • A consistent finding of an extra copy of chromosome 12 was noted.

Implications:

  • The extra chromosome 12 may be a key factor in mesenchymal tumor development.

Related Experiment Videos

  • This finding could indicate a shared embryonic origin for certain tumors.
  • Further research into chromosome 12's role in tumorigenesis is warranted.