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Related Experiment Videos

Pasteurella multocida chorioamnionitis from vaginal transmission.

G P Wong1, N Cimolai, J E Dimmick

  • 1Department of Obstetrics, Gynecology, University of British Columbia, Vancouver, Canada.

Acta Obstetricia Et Gynecologica Scandinavica
|July 1, 1992
PubMed
Summary
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Pasteurella multocida caused chorioamnionitis in a twin pregnancy after prolonged membrane rupture. One twin died from infection, while the other remained unaffected, highlighting risks of ascending bacterial infections.

Area of Science:

  • Obstetrics and Gynecology
  • Infectious Diseases
  • Neonatology

Background:

  • Twin pregnancies present unique challenges in obstetric care.
  • Chorioamnionitis, an infection of the fetal membranes, can lead to severe maternal and neonatal complications.
  • Ascending infections are a common pathway for microbial invasion during pregnancy.

Observation:

  • A 21-year-old primigravida with a twin pregnancy developed Pasteurella multocida chorioamnionitis at 27 weeks gestational age.
  • Infection followed prolonged rupture of membranes.
  • One twin, located in a separate sac proximal to the cervix, was infected and died shortly after birth.
  • The second twin remained uninfected.

Findings:

  • Pasteurella multocida was identified as the causative agent of chorioamnionitis.

Related Experiment Videos

  • The infection likely resulted from ascending bacteria from asymptomatic vaginal colonization.
  • The location and sac separation influenced the outcome of the twin pregnancy.

    • Implications:

    • This case underscores the potential severity of Pasteurella multocida infections in pregnancy.
    • Early recognition and management of prolonged membrane rupture are crucial in twin gestations.
    • Understanding the pathogenesis of ascending infections is vital for preventing adverse neonatal outcomes.