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Functional significance of cyclic AMP secretion in cerebral cortex
1Department of Neurology, Children's Hospital, Boston, MA 02115.
Brain Research Bulletin
|September 1, 1992
Abstract:
Cyclic AMP secretion in response to beta adrenergic receptor stimulation has been demonstrated in glioma-derived cell lines, in cerebral cortex in dissociated cell culture, and in the frontal cortex of living animals. The possible functions of cAMP secretion are considered; in particular, a role for this phenomenon in mediating some of the actions of norepinephrine as a neuromodulator in cerebral cortex.