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Published on: July 14, 2021
[Systolic and diastolic load of right heart and right bundle block]
Insights
Right bundle branch block (RBBB) decreases with age in children and is linked to right ventricle hypertrophy. RBBB in healthy individuals may represent a normal variant of fetal and childhood right ventricular hypertrophy.
Area of Science:
- Cardiology
- Electrophysiology
Context:
- Right bundle branch block (RBBB) prevalence varies across age groups and cardiac conditions.
- Studies indicate RBBB is common in atrial septal defects and right ventricular pressure overload.
- Experimental models in dogs show increased RBBB incidence with right heart loading.
Purpose:
- To analyze the frequency and determinants of RBBB in healthy subjects and patients with congenital and acquired heart conditions.
- To investigate the relationship between RBBB and right ventricular hypertrophy and loading.
- To explore the potential of RBBB as an indicator of persistent fetal/childhood physiological right ventricular hypertrophy.
Summary:
- Analysis of ECG and VCG in 818 subjects revealed RBBB frequency decreases with age, with 8.9% in healthy adults.
- RBBB is highly prevalent in atrial septal defects (82.5%) and right ventricular tension loading, decreasing with left ventricle loading and hypertrophy.
- Experiments in dogs demonstrated a steady increase in RBBB with right heart loading, irrespective of hypertrophy type, suggesting RBBB reflects persistent physiological right ventricular hypertrophy.
Impact:
- Findings suggest RBBB in healthy individuals may represent a normal variant of right ventricular hypertrophy.
- The persistence or disappearance of RBBB is influenced by the interplay between left and right ventricular electromotive forces.
- This research provides insights into the electrophysiological basis of RBBB in various cardiac states.
Abstract:
Analysing the Ecg and VCG of 818 subjects, healthy or with different congenital and acquired cardiopaties, the frequency of right bundle branch block (RBBB) is established to decrease with the increase in age of children, and is observed to be 8.9% in healthy adults. The right bundle block is observed in 82.5% of the patients with atrial septal defect and quite often in patients with right ventricle tension loading, gradually decreasing with the level of the left ventricle loading, as well as with the development of extreme right ventricle hypertrophy. Out of 50 experiments with dogs with acute and chronic right heart tension loading it is evident that the number of certain and marginal (uncertain) cases with RBBB steadily increases. At the same time this increase cannot be connected with the type of loading, in dogs in which dilatation of the right ventricle is presented as well as in others with light or marked hypertrophy. Besides, under the same conditions and durations of loading some hearts exhibit RBBB, while others do not. What has been stated before gives enough grounds to accept that RBBB in healthy subjects, as well as in patients with congenital and acquired cardiopaties manifests the electromotive tension (EMT) of persistent from foetal and children-age more pronounced physiological hypertrophy (as normal variant) of the basal part of the right ventricle. Whether the picture of RBBB is retained, pronounced or disappears is determined by the correlation between the quantity and the time-manifestation of EMT of the left ventricle and of the corps part of the right ventricle.
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