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Deep negative T waves associated with reversible left ventricular dysfunction in acute adrenal crisis
Heart and Vessels
|January 1, 1992
Summary
Acute adrenal crisis can cause reversible heart dysfunction and deep negative T waves. These cardiac changes, linked to isolated adrenocorticotrophic hormone deficiency, resolve with corticosteroid treatment.
Area of Science:
- Cardiology
- Endocrinology
Background:
- Acute adrenal crisis, often due to isolated adrenocorticotrophic hormone deficiency, can present with unusual symptoms.
- Cardiac manifestations in adrenal crisis are not widely recognized, especially without typical cardiac disease indicators.
Observation:
- Two patients presented with acute adrenal crisis and significant electrocardiographic (ECG) changes, specifically deep negative T waves.
- Both patients exhibited reversible left ventricular dysfunction, primarily affecting the apex, without any preceding cardiac symptoms.
Findings:
- Left ventricular dysfunction and deep negative T waves resolved within 1-2 weeks and 4 weeks, respectively, following corticosteroid administration.
- The cardiac abnormalities were directly associated with the acute adrenal crisis and resolved upon its treatment.
Implications:
- Clinicians should consider acute adrenal crisis in patients presenting with unexplained left ventricular dysfunction and deep negative T waves, even without cardiac symptoms.
- Early recognition and treatment of adrenal crisis are crucial for resolving these cardiac manifestations and preventing potential complications.