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Perianal Paget's disease: report of five cases
S Goldman1, T Ihre, U Lagerstedt
1Department of Surgery, Södersjukhuset, Stockholm, Sweden.
International Journal of Colorectal Disease
|September 1, 1992
Summary
Paget
Area of Science:
- Gastroenterology
- Oncology
- Dermatology
Background:
- Paget's disease of the anus is a rare perianal disorder.
- It is frequently linked to invasive carcinoma, impacting prognosis.
Observation:
- This study presents five cases of perianal Paget's disease.
- Underlying adenocarcinoma was identified in the anorectum in two cases.
- One case showed adenocarcinoma in sweat gland ducts.
Findings:
- Adenocarcinoma was found in the anorectum in 2/5 cases.
- One patient developed anorectal adenocarcinoma 4 years post-Paget diagnosis.
- No underlying adenocarcinoma was found in only one case.
Implications:
- Early detection and management of associated anorectal adenocarcinoma are crucial.
- The strong association highlights the need for thorough oncological evaluation.
- Understanding this link improves patient outcomes for perianal Paget's disease.