Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Aging of heart function in man].

C Swine1

  • 1Service de Gériatrie, Cliniques Universitaires UCL de Mont-Godinne, Yvoir, Belgique.

Presse Medicale (Paris, France : 1983)
|July 22, 1992
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Early diagnosis of dehydration in hospitalized geriatric patients using clinical and laboratory criteria.

European geriatric medicine·2021
Same author

Functional status and medium-term prognosis of very elderly patients after an ICU stay: a prospective observational study.

Minerva anestesiologica·2015
Same author

Evaluation of the Xpert MRSA assay for rapid detection of methicillin-resistant Staphylococcus aureus from nares swabs of geriatric hospitalized patients and failure to detect a specific SCCmec type IV variant.

European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology·2010
Same author

Predicting functional adverse outcomes in hospitalized older patients: a systematic review of screening tools.

The journal of nutrition, health & aging·2010
Same author

Risk factors predicting later functional decline in older hospitalized patients.

Acta clinica Belgica·2009
Same author

Ecthyma gangrenosum in a non-neutropaenic, elderly patient: case report and review of the literature.

Acta clinica Belgica·2009
Same journal

Predictive analytics and risk stratification models in internal medicine: from risk scores to real-time machine learning.

Presse medicale (Paris, France : 1983)·2026
Same journal

Artificial Intelligence in skin disease therapeutics: from drug discovery to personalized treatment pathways.

Presse medicale (Paris, France : 1983)·2026
Same journal

AI in clinical diagnostics in dermatology: applications, validation, and real-world use cases.

Presse medicale (Paris, France : 1983)·2026
Same journal

Artificial Intelligence in medical research and publishing: progress, risks, and future perspectives.

Presse medicale (Paris, France : 1983)·2026
Same journal

Ethical, legal, and regulatory challenges in AI-based healthcare tools.

Presse medicale (Paris, France : 1983)·2026
Same journal

Decision-making for clinicians.

Presse medicale (Paris, France : 1983)·2026
See all related articles

Aging preserves cardiac function through adaptive mechanisms. Despite arterial stiffening and reduced heart rate, the heart maintains output at rest and during exercise via left ventricular hypertrophy and atrial compensation.

Area of Science:

  • Cardiovascular Physiology
  • Gerontology
  • Cardiac Aging

Context:

  • Normal aging involves significant changes in cardiovascular structure and function.
  • Arterial elasticity decreases, leading to increased impedance and ventricular afterload.
  • Left ventricular diastolic function is altered due to delayed relaxation and changes in muscle properties.

Purpose:

  • To investigate the impact of aging on cardiac function at rest and during exercise.
  • To identify age-related primary changes and secondary homeostatic adaptations in the cardiovascular system.
  • To understand how the aging heart maintains cardiac output despite physiological alterations.

Summary:

  • At rest, cardiac output is maintained by left ventricular hypertrophy and increased atrial contribution to filling, despite reduced arterial elasticity.

Related Experiment Videos

  • During dynamic exercise, heart rate declines but ejection volume increases, preserving cardiac output, supported by Starling's mechanism.
  • Isometric exercise elicits compensatory atrial augmentation of filling when ejection fraction decreases and end-systolic volume increases.

    • Impact:

    • The aging heart demonstrates remarkable resilience, maintaining cardiac work through compensatory mechanisms.
    • Understanding these adaptations is crucial for managing cardiovascular health in the elderly population.
    • Identifies key physiological changes and adaptive responses that preserve cardiac function throughout the lifespan.