Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Hepatitis A outbreak in a kindergarten].

C Conzelmann-Auer1, U Ackermann-Liebrich, C Herzog

  • 1Institut für Sozial- und Präventivmedizin, Universität Basel.

Schweizerische Medizinische Wochenschrift
|October 17, 1992
PubMed
Summary

A hepatitis A outbreak in a kindergarten spread person-to-person, originating from an imported case. Timely immunoglobulin administration was protective, while delayed or no immunization led to widespread illness.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Effects of early childhood otitis media and ventilation tubes on psychosocial wellbeing - A prospective cohort study within the Danish National Birth Cohort.

International journal of pediatric otorhinolaryngology·2020
Same author

Laboratory Setup for Scanning-Free Grazing Emission X-ray Fluorescence.

Analytical chemistry·2017
Same author

A flexible setup for angle-resolved X-ray fluorescence spectrometry with laboratory sources.

The Review of scientific instruments·2016
Same author

Tetrodotoxin-sensitive α-subunits of voltage-gated sodium channels are relevant for inhibition of cardiac sodium currents by local anesthetics.

Naunyn-Schmiedeberg's archives of pharmacology·2016
Same author

Results in laparoscopic living donor nephrectomy: a multicentric experience.

Transplantation proceedings·2013
Same author

Pediatric liver transplantation experience and outcome in Chile.

Transplantation proceedings·2013

Area of Science:

  • Epidemiology
  • Virology
  • Public Health

Context:

  • A kindergarten in Basle experienced a hepatitis A outbreak in November/December 1990.
  • The outbreak involved children, family members, and friends, necessitating an investigation into its source and spread.

Purpose:

  • To investigate the source, extent, and person-to-person transmission of hepatitis A.
  • To evaluate the effectiveness of hygienic measures and immunoglobulin prophylaxis.

Summary:

  • An adult returning from Mexico imported the hepatitis A virus, leading to an outbreak primarily within a kindergarten.
  • The investigation identified 20 clinical cases and 5 subclinical infections among 147 individuals.
  • Hygienic measures were effective, and timely immunoglobulin administration prevented further transmission, while delayed or no prophylaxis resulted in significant illness.

Impact:

  • Demonstrates the efficacy of public health interventions, including hygiene and immunoglobulin, in controlling viral outbreaks.
  • Highlights the importance of prompt post-exposure prophylaxis in preventing the spread of hepatitis A.
  • Provides insights into the transmission dynamics of hepatitis A in a community setting.

Related Experiment Videos