Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Small B-cell lymphoid neoplasms with coexisting T-cell lymphomas.

J G Strickler1, T W Amsden, P J Kurtin

  • 1Department of Laboratory Medicine and Pathology, Mayo Clinic, Minneapolis, Minnesota.

American Journal of Clinical Pathology
|October 1, 1992
PubMed
Summary

Two patients showed a rare composite lymphoma, with both small B-cell lymphocytic neoplasms and T-cell lymphomas in the same lymph node. This finding highlights the coexistence of these distinct lymphoid malignancies.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Systemic amyloidosis from A (AA) to T (ATTR): a review.

Journal of internal medicine·2020
Same author

Phase I trial of rituximab, cladribine, and temsirolimus (RCT) for initial therapy of mantle cell lymphoma.

Annals of oncology : official journal of the European Society for Medical Oncology·2018
Same author

Education and imaging. Gastrointestinal: Gastric involvement in disseminated lymphadenopathic Kaposi sarcoma.

Journal of gastroenterology and hepatology·2015
Same author

Phase I trial of rituximab, cladribine, and temsirolimus (RCT) for initial therapy of mantle cell lymphoma.

Annals of oncology : official journal of the European Society for Medical Oncology·2014
Same author

Denileukin diftitox in combination with rituximab for previously untreated follicular B-cell non-Hodgkin's lymphoma.

Leukemia·2011
Same author

Chronic lymphoproliferative disorder of natural killer cells: a distinct entity with subtypes correlating with normal natural killer cell subsets.

Leukemia·2010

Area of Science:

  • Hematology
  • Oncology
  • Pathology

Background:

  • Composite lymphomas involving both B-cell and T-cell neoplasms are rare.
  • Understanding the coexistence of distinct lymphoid malignancies is crucial for accurate diagnosis and treatment.

Observation:

  • Two cases of composite lymphoma were identified in lymph node biopsies.
  • Case 1: Chronic lymphocytic leukemia (B-cell) with coexisting large-cell lymphoma (T-cell phenotype).
  • Case 2: Small lymphocytic lymphoma (B-cell phenotype) with coexisting small-cell pleomorphic lymphoma (T-cell phenotype).

Findings:

  • Both patients' lymph node specimens met strict criteria for composite lymphomas.
  • The first patient's presentation was consistent with Richter's transformation of chronic lymphocytic leukemia.

Related Experiment Videos

  • The study demonstrates that small B-cell lymphocytic neoplasms can coexist with T-cell lymphomas.

    • Implications:

    • These findings expand the understanding of composite lymphoma presentations.
    • Highlights the importance of thorough immunophenotypic analysis in lymph node biopsies.
    • May influence diagnostic criteria and therapeutic strategies for complex lymphoid neoplasms.